Spain / Battles, Knights..The Battle of Pavía - Francis I of France, suffered his most devastating defeat at the Battle of Pavia on 24 February 1525, during part of the continuing Italian Wars known as the Four Years' War. Francis was actually captured by the forces of Charles V . Francis I was held captive in Madrid. In a letter to his mother he wrote, "Of all things, nothing remains to me but honour and life, which is safe." Desembarco de Francisco I en el puerto de Valencia.