Supernatural - Dean Winchester's behind you. - Remember when those other hunters killed Sam? // WALT: He made us and we just snuffed his brother, you idiot. You want to spend the rest of your life knowing Dean Winchester’s on your ass, ‘cause I don’t.
This is honestly one of the saddest moments. Dean looks absolutely heart broken to have watched his brother die (again) and they know that they have to kill Dean because no way would they be able to escape Dean Winchester after they killed Sammy